Water → HCID 23457302, compound

Participants

Reaction Steps

To a solution of 22.3 g of 2-(2-dimethylaminoethyl)-3-methyl-1-phenylindole in 160 ml of tetrahydrofuran there are added 6.1 g of sodium borohydride. 26.3 ml of boron trifluoride diethyl etherate are added dropwise at room temperature. The mixture is then heated at reflux for one hour, cooled to 0° and 15 ml of water are slowly added dropwise. The mixture is then poured onto ice-water and the resulting boron complex is extracted with ethyl acetate.

Provenance & Evidence