反应详情

2-(4-Methylpyrid-2-ylmethyl)isothiourea dihydrochloride can be prepared in accordance with the method described in Example 1 for the preparation of 2-(pyrid-2-ylmethyl)isothiourea dihydrochloride. Using 2-chloromethyl-4-methylpyridine hydrochloride (376 g) and thiourea (185 g) as the starting materials, 2-(4-methylpyrid-2-ylmethyl)isothiourea dihydrochloride (411 g), melting at 220° C., is obtained.