Nitric Acid → HCID 70560765, compound

HRID 1680216Notes

Reaction equation

HRID 1680216 reaction equation
[N+:1]([O-:4])([OH:3])=[O:2].[Cl:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([Cl:12])[C:7]=1[S:13][CH:14]([CH2:21][CH2:22][C:23]1[S:24][C:25]([Cl:28])=[CH:26][CH:27]=1)[CH2:15][N:16]1[CH:20]=[CH:19][N:18]=[CH:17]1>CCOCC>[N+:1]([O-:4])([OH:3])=[O:2].[Cl:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([Cl:12])[C:7]=1[S:13][CH:14]([CH2:21][CH2:22][C:23]1[S:24][C:25]([Cl:28])=[CH:26][CH:27]=1)[CH2:15][N:16]1[CH:20]=[CH:19][N:18]=[CH:17]1

Participants

4

Reactant 2

HCID 944Nitric AcidHCID 12895741HCID 12895741, compound

Product 1

HCID 70560765HCID 70560765, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Nitric acid (70%; d=1.42) is added dropwise to a stirred solution of 2.0 g of 1-[2-(2,6-dichlorophenylthio)-4-(5-chloro-2-thienyl)-n-butyl]imidazole in 30 ml of anhydrous ether until precipitation is complete. The product is filtered off, washed with ether, air dried and recrystallized from ethanol to yield 1-[2-(2,6-dichlorophenylthio)-4-(5-chloro-2-thienyl)-n-butyl]imidazole nitrate mp 147°-148.5° (dec.)

Workup

  1. filtrationThe product is filtered off
  2. washwashed with ether, air
  3. customdried
  4. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-2c9fd8ea6660422eacf7702651e4450a
Source dataset
uspto-grants-1981_06
Patent number
US04272545

Reaction notes

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