Sodium Hydroxide → HCID 12898561, compound

Participants

Reaction Steps

Combine methyl 2-[4-(2-aminohexafluoro-2-propyl)-2,6-dimethylphenoxy]acetate (7.2 g=20 mmol) with 150 ml ethanol and 30 ml 1.0 N sodium hydroxide. Reflux 30 minutes and concentrate. Add 30 ml 1 N HCl and extract with ether. Dry and concentrate the ether. Sublime at 130° C./0.1 mm pressure to obtain as a white solid, 2-[4-(2-aminohexafluoro-2-propyl)-2,6-dimethylphenoxy]acetic acid, m.p. 138° C.

Provenance & Evidence