Methanol → HCID 54570347, compound

HRID 1680273Notes

Reaction equation

HRID 1680273 reaction equation
[OH-].[Na+].[C:3]([C:11]1[CH:12]=[C:13]2[C:17](=[CH:18][C:19]=1[O:20][CH3:21])[CH:16]([C:22]([OH:24])=[O:23])[CH2:15][CH2:14]2)(=[O:10])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[CH3:25]O>>[CH3:25][O:23][C:22]([CH:16]1[C:17]2[C:13](=[CH:12][C:11]([C:3](=[O:10])[C:4]3[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=3)=[C:19]([O:20][CH3:21])[CH:18]=2)[CH2:14][CH2:15]1)=[O:24]

Participants

4

Reactant 3

HCID 887MethanolHCID 14798Sodium HydroxideHCID 23457893HCID 23457893, compound

Product 1

HCID 54570347HCID 54570347, compound

Procedure

Analogously to the description in Example 2, 4.7 g of 5-benzoyl-6-methoxy-indane-1-carboxylic acid methyl ester and 20 ml of N sodium hydroxide solution in 50 ml of methanol give 5-benzoyl-6-methoxy-indane-1-carboxylic acid of melting point 126°-128° C. (from ether-petroleum ether).

Sources & evidence

ORD record
ord-b294ac82ab02447b8566f96ad4eefe63
Source dataset
uspto-grants-1981_06
Patent number
US04272547

Reaction notes

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