Hydrogen Bromide → HCID 178419601, compound

Participants

Reaction Steps

N-Benzyloxycarbonyl-Ng -nitro-L-arginyl-L-proline methyl ester (16.3 g., 35.1 mmoles) is treated with 30% hydrobromic acid in glacial acetatic acid (50 ml) for one hour and at room temperature. Dry diethyl ether (ca. 500 ml) is added to give a pale yellow very hygroscopic solid. The product is not characterized further due to the very hygroscopic nature. It is dried in vacuo over KOH and used for the next reaction.

Provenance & Evidence