HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexamethylphosphoramide → 1-Ethoxyethyl 4-(hexadecylamino)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexamethylphosphoramide | HCID 12679 | — |
| Reactant | Ethane, 1-chloro-1-ethoxy- | HCID 23478 | — |
| Reactant | Cetaben Sodium | HCID 23703815 | — |
| Solvent | Water | HCID 962 | — |
| Product | 1-Ethoxyethyl 4-(hexadecylamino)benzoate | HCID 23457774 | — |
Reaction Steps
A mixture of 22.0 g. of ethyl 1-chloroethyl ether, 77.0 g. of sodium 4-(hexadecylamino)benzoate and 250 ml. of hexamethylphosphoramide is stirred at 20° C. for 24 hours. After slow addition of water to the crystallization point and standing for 3 hours, the acetal ester is collected on a filter.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04272546 |
| Source dataset | uspto-grants-1981_06 |
| ORD ID | ord-a9bcaa79c91d486eacf6741dcaca5613 |
| Source note | uspto-grants-1981_06 |