HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chlorobenzaldehyde → HCID 12640216, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chlorobenzaldehyde | HCID 11477 | — |
| Reactant | Methyl 5-aminopyridine-2-carboxylate | HCID 12457877 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 12640216 | HCID 12640216 | — |
Reaction Steps
The starting material is prepared as follows: The mixture of 30.44 g of 5-aminopyridine-2-carboxylic acid methyl ester, 30.9 g of m-chlorobenzaldehyde and 400 ml of benzene is refluxed on a water-trap for 3 days. It is evaporated and the residue recrystallized from benzene/ethylacetate/diethyl ether, to yield the 5-(m-chlorobenzylideneamino)-pyridine-2-carboxylic acid methyl ester melting at 139°-142°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04273779 |
| Source dataset | uspto-grants-1981_06 |
| ORD ID | ord-c3fa626a9daa438a950549ee5452c374 |
| Source note | uspto-grants-1981_06 |