HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Ethyl 4-(1H-indol-1-yl)butanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | HCID 10241973 | HCID 10241973 | — |
| Product | Ethyl 4-(1H-indol-1-yl)butanoate | HCID 19024819 | — |
Reaction Steps
Phosphorus oxychloride (10 ml) was added dropwise with cooling to a stirred solution of 1-(3-carboxypropyl)indole (100 g) in ethanol (750 ml). The solution was heated under reflux for 8 hours and then evaporated. The residue was distilled to give 1-(3-ethoxycarbonylpropyl)indole (95.0 g), b.p. 164°-170° C./2 m.m.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04273782 |
| Source dataset | uspto-grants-1981_06 |
| ORD ID | ord-acf9f6e179c246908b2c4ef391dbdf60 |
| Source note | uspto-grants-1981_06 |