Ammonium Hydroxide → HCID 70575784, compound

Participants

Reaction Steps

Concentrated ammonium hydroxide (10 ml, S.G. 0.880) was added to a solution of 1-ethoxycarbonylmethyl-3-(1-imidazolylmethyl) indole (0.50 g) in ethanol (5 ml) and the mixture was stirred at room temperature for 2 hours. The solid was filtered off, washed with water, dried and crystallised from ethanol/petrol (b.p. 60°-80° C.) to give 1-carbamoylmethyl-3-(1-imidazolylmethyl)indole (0.24 g), m.p. 211°-212° C. Found: C, 65.65; H, 5.58; N, 21.69. C14H14N4O requires: C, 66.12; H, 5.55; N, 22.04.

Provenance & Evidence