Hydrogen Peroxide → HCID 70575833, compound

Participants

Reaction Conditions

Reaction Steps

1-(4-Cyanobenzyl)-3-(1-imidazolylmethyl)indole (1.0 g) was dissolved in ethanol (10 ml) and 30% hydrogen peroxide (5 ml) and 6 N sodium hydroxide (5 ml) were added. The resulting mixture was stirred for 2 hours at 50° C. and then poured into water. The solid product was filtered off, washed with water and crystallised from ethanol to give 1-(4-carbamoylbenzyl)-3-(1-imidazolylmethyl)indole (0.65 g), m.p. 173°-175° C. Found: C, 72.63; H, 5.54; N, 16.29. C20H18N4O4 requires: C, 72.71; H, 5.49; N, 16.96.

Provenance & Evidence