反应详情

温度

25 °C

A mixture of 2-(2-nitro-1-propenyl)-benzoic acid methyl ester (1.6 g, described in Example 28), sodium acetate (1.1 g) and 2,2-diethoxyethanamine (1.25 ml) in acetonitrile (20 ml) is stirred at 25° C. for 18 hr and evaporated. The residue is dissolved in ethyl acetate. The organic solution is washed with 1 N hydrochloric acid and brine, dried and evaporated to give the title compound as a mixture of two isomers (2.5 g).

1. customevaporated
2. dissolutionThe residue is dissolved in ethyl acetate
3. washThe organic solution is washed with 1 N hydrochloric acid and brine
4. customdried
5. customevaporated