2,2-Diethoxyethylamine → HCID 23456484, compound

Participants

Reaction Conditions

Reaction Steps

A suspension of 2-(2-nitro-1-butenyl)-benzoic acid methyl ester (49 g, described in Example 29) sodium acetate (27.5 g) and 2,2-diethoxyethanamine (44 g) in acetonitrile (1000 ml) is stirred at 25° C. for 24 hr and filtered. The filtrate is evaporated and the residue is dissolved in chloroform. The organic solution is washed with water, 10% hydrochloric acid and brine, dried and evaporated to obtain the title compound as a mixture of isomers (67 g).

Provenance & Evidence