Hydrogen Bromide → HCID 70567512, compound

Participants

Reaction Steps

To 3.58 grams of methyl carbobenzoxy-L-phenylalanyl-3-amino-1-adamantanecarboxylate dissolved in 10 ml of acetic acid is added 15 ml of a 5 M solution of hydrogen bromide in acetic acid, and the reaction mixture is allowed to stand for one hour at room temperature. The solvent is removed by distillation under vacuum and the residue is shaken with two 100 ml portions of hexane, then 100 ml of ether, to give methyl L-phenylalanyl-3-amino-1-adamantanecarboxylate hydrobromide which has the following structural formula ##STR14##

Provenance & Evidence