Bromo(phenyl)acetic acid → HCID 70512580, compound

HRID 1680632Notes

Reaction equation

HRID 1680632 reaction equation
Br[CH:2]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[C:3]([OH:5])=[O:4].[K].[SH:13][C:14]1[S:15][C:16]2[C:21]([N:22]=1)=[CH:20][CH:19]=[CH:18][N:17]=2>CC(C)=O>[N:22]1[C:21]2[C:16](=[N:17][CH:18]=[CH:19][CH:20]=2)[S:15][C:14]=1[S:13][CH:2]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[C:3]([OH:5])=[O:4]

Participants

5

Reactant 3

HCID 97919Bromo(phenyl)acetic acidHCID 5462222PotassiumHCID 178527801HCID 178527801, compound

Product 1

HCID 70512580HCID 70512580, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

6.5 g. (0.03 moles) α-bromophenylacetic acid and 6.2 g. (0.03 moles) potassium salt of 2-mercaptothiazolo[5,4-b]pyridine are suspended in 200 ml. acetone and the mixture is stirred at room temperature overnight. The mixture is filtered and the filtrate concentrated to dryness. The resulting compound is an oil and is not isolated.

Workup

  1. filtrationThe mixture is filtered
  2. concentrationthe filtrate concentrated to dryness
  3. customis not isolated

Sources & evidence

ORD record
ord-eaee6c31378847dfaf5c962a08ac63fa
Source dataset
uspto-grants-1981_06
Patent number
US04275065

Reaction notes

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