HCID 22807221, compound → HCID 70570162, compound

Participants

Reaction Steps

(5R)-7-Oxo-3-vinyl-4-oxa-1-azabicyclo[3.2.0]hept-2-ene (2.4 mmole) and p-benzyloxycarbonylaminophenyl mercaptan (0.775 g) were converted into the title compound using the process described in Example 1. The title compound was obtained as a colourless gum (63 mg), [α]D25 =34.6° (c 1.0, CHCl3), (Found: M+, 396.1136; C21H20N2O4S requires 396.1144). νmax (CHCl3): 3370, 3240, 1790, 1735, 1700, 1590, 1515 cm-1. δ(CDCl3): 2.71 (1H, d, J 16 Hz), 3.10-3.60 (4H, complex), 4.22 (1H, d, J 15 Hz), 4.38 (1H, t, J 7 Hz), 5.16 (2H, s), 5.32 (1H, d, J 2 Hz), 6.90 (1H, br.s), 7.10-7.45 (9 H, complex). m/e: 396 (M+, 6%), 138 (41), 108(20), 107(12), 96(46), 91(100).

Provenance & Evidence