HCID 57291236, compound → HCID 131712269, compound

HRID 1680670Notes

Reaction equation

HRID 1680670 reaction equation
CO[C:3](=[O:24])[CH2:4][CH:5]([NH:20]C(=O)C)[CH2:6][CH:7]([OH:19])[CH2:8][CH:9]([NH:15]C(=O)C)[CH2:10][C:11]([O:13][CH3:14])=[O:12].[ClH:25].Cl.[CH3:27][O:28][C:29](=[O:44])[CH2:30][CH:31]([NH2:43])[CH2:32][C:33](=[O:42])[CH2:34][CH:35]([NH2:41])[CH2:36]C(OC)=O>>[ClH:25].[ClH:25].[ClH:25].[ClH:25].[CH3:27][O:28][C:29](=[O:44])[CH2:30][CH:31]([NH2:43])[CH2:32][CH:33]([OH:42])[CH2:34][CH:35]([NH2:41])[CH2:36][C:3](=[O:24])[CH2:4][CH:5]([NH2:20])[CH2:6][CH:7]([OH:19])[CH2:8][CH:9]([NH2:15])[CH2:10][C:11]([O:13][CH3:14])=[O:12]

Participants

3

Reactant 2

HCID 57291236HCID 57291236, compoundHCID 86737814HCID 86737814, compound

Product 1

HCID 131712269HCID 131712269, compound

Procedure

When an equivalent quantity of 3,7-diacetylamino-5-hydroxy-1,9-nonanedioic acid dimethyl ester is substituted for the N-acetyl-3-aminoglutaric acid dimethyl ester of Example 6 and the procedures detailed therein substantially repeated there is obtained 3,7,11,15-tetramino-5,13-dihydroxy-9-oxo-1,17 heptadecanedioic acid dimethyl ester tetrahydrochloride which has the following structural formula ##STR28##

Sources & evidence

ORD record
ord-94e98c2b582d4c29b02748a0687b893e
Source dataset
uspto-grants-1981_06
Patent number
US04275192

Reaction notes

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