反应详情

A mixture of 3.06 grams of (1-ethyl-2-methylindol-3-yl) (2-carboxyphenyl)ketone, 2.7 grams of 2,3-diphenylindolizine and 10 ml. of acetic anhydride was heated at about 50° C. for 107 minutes. The reaction mixture was cooled and filtered and the obtained product was recrystallized from a toluene-heptane mixture. The 3.3 grams of product were recrystallized from a toluene-heptane mixture to a constant melting point of 227°-227.5° C. A chloroform solution of the product when applied to silica gel produced a blue color.

1. temperatureThe reaction mixture was cooled
2. filtrationfiltered
3. customthe obtained product was recrystallized from a toluene-heptane mixture
4. customThe 3.3 grams of product were recrystallized from a toluene-heptane mixture to a constant melting point of 227°-227.5° C
5. customproduced a blue color