Water → HCID 86737819, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 1.76 g; 6.5 mmol of compound VI in 35 ml of acetic acid there were added 140 ml of water. The solution was then heated at 100° C. for 1 hour. The solvent was then evaporated off and the residue was recrystallized from carbon tetrachloride to give 1.64 g (yield 98%) of 4-O-methyl-2,3,6-trideoxy-3-trifluoroacetamido-α-L-ribohexopyranose (VII); m.p. 113°-115° C.; [α]D23° =-61.5° (c=0.5 in CHCl3); mass spectrum; m/e 257 (M+). The p.m.r. spectrum showed absoption at: 1.27 (d, CH3 --C--5), 2.96 (dd, J=9.5 and 4.0 Hz, C--4--H), 3.44 (s, CH3O), 4.00 (dq, J=6.5 and 9.5 Hz, C--5--H), 4,69 (m, C--3--H) and 5.32 (broad s, WH =6.0 Hz, C--1--H).

Provenance & Evidence