Hydrogen Bromide → 4-Hydroxybenzoic Acid

Participants

Reaction Steps

Next, the 4-methoxybenzoic acid (IV) was digested with HBr (20 ml) and glacial acetic acid (40 ml) overnight. Most of the acetic acid was distilled off and the remaining mixture was diluted with water. The precipitated benzoic acid was extracted in ether; the ether layer was dried with anhydrous MgSO4, filtered and rotary evaporated to produce 11.0 g of the 4-hydroxybenzoic acid (V).

Provenance & Evidence