2-(2,3-Dichlorophenoxy)acetamidine hydrochloride → 2-(2,3-Dichlorophenoxy)acetamidine

HRID 1681021Notes

Reaction equation

HRID 1681021 reaction equation
Cl.[Cl:2][C:3]1[C:13]([Cl:14])=[CH:12][CH:11]=[CH:10][C:4]=1[O:5][CH2:6][C:7]([NH2:9])=[NH:8]>[OH-].[Na+]>[Cl:2][C:3]1[C:13]([Cl:14])=[CH:12][CH:11]=[CH:10][C:4]=1[O:5][CH2:6][C:7]([NH2:9])=[NH:8]

Participants

3

Reactant 1

HCID 197362082-(2,3-Dichlorophenoxy)acetamidine hydrochloride

Product 1

HCID 105130432-(2,3-Dichlorophenoxy)acetamidine

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

8.0 g (0.031 mole) of 2-(2,3-dichlorophenoxy)actamidine hydrochloride are suspended in sodium hydroxide solution and extracted with chloroform. The organic extract is concentrated to dryness under reduced pressure. The solid residue is washed with hexane and dried; it is used in the next step without further purification. Yld: 6.7 g (98%), m.p. 104°-108° C.

Workup

  1. extractionextracted with chloroform
  2. extractionThe organic extract
  3. concentrationis concentrated to dryness under reduced pressure
  4. washThe solid residue is washed with hexane
  5. customdried
  6. customit is used in the next step without further purification

Sources & evidence

ORD record
ord-a303eee316024e4c9546773008bc8b3c
Source dataset
uspto-grants-1992_12
Patent number
US05167949

Reaction notes

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