HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminopyrazine-2-carbonitrile → 4-Amino-2-[(2,3-dichlorophenoxy)methyl]pteridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminopyrazine-2-carbonitrile | HCID 817699 | — |
| Reactant | 2-(2,3-Dichlorophenoxy)acetamidine | HCID 10513043 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-Amino-2-[(2,3-dichlorophenoxy)methyl]pteridine | HCID 10519841 | — |
Reaction Steps
Obtained using the procedure described in section c of Example 2, starting with 3.6 g (0.030 mole) of 3-amino-2-pyrazinecarbonitrile and 6.6 g (0.030 mole) of 2-(2,3-dichlorophenoxy)acetamidine in 100 ml of absolute ethanol. Refluxing time: 14 hours. Yld: 8.1 g (84%), m.p. 216°-218° C. (ethanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05167949 |
| Source dataset | uspto-grants-1992_12 |
| ORD ID | ord-115d2b8fb78643f8ad0dfca45529aa94 |
| Source note | uspto-grants-1992_12 |