Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1681024Generated: October 25, 2026

Ethanol → 2-Benzyloxymethyl-4(3H)-pteridinone

https://huagongshe.com/reaction/1681024

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
Reactant4-Amino-2-(benzyloxymethyl)pteridineHCID 10778229—
SolventSodium HydroxideHCID 14798—
Product2-Benzyloxymethyl-4(3H)-pteridinoneHCID 135461697—

Reaction Conditions

Temperature80 °C

Reaction Steps

Obtained using the procedure described in section b of Example 9, starting with 10.0 g (0.037 mole) of crude 4-amino-2-(benzyloxymethyl)pteridine in 300 ml of 5% aqueous sodium hydroxide. Heating time, 2 hours at 80° C. Yld: 8.2 g (83%), m.p. 157°-159° C. (ethanol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05167949
Source datasetuspto-grants-1992_12
ORD IDord-82026c598473433ca2da58396cb7ae37
Source noteuspto-grants-1992_12