HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminopyrazine-2-carbonitrile → 4-Amino-2-(methoxymethoxymethyl)pteridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminopyrazine-2-carbonitrile | HCID 817699 | — |
| Reactant | 2-(Methoxymethoxy)acetamidine | HCID 10534653 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-Amino-2-(methoxymethoxymethyl)pteridine | HCID 10680492 | — |
Reaction Steps
Obtained using the procedure described in section c of Example 2, starting with 12.0 g (0.10 mole) of 3-amino-2-pyrazinecarbonitrile and 18.0 g (0.15 mole) of 2-(methoxymethoxy)acetamidine in 400 ml of absolute ethanol. Refluxing time: 4 hours. Yld: 15.8 g (71%), m.p. 129°-131° C. (ethanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05167949 |
| Source dataset | uspto-grants-1992_12 |
| ORD ID | ord-f5b9f4ca83c14489be63e7f802846c25 |
| Source note | uspto-grants-1992_12 |