HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → 4-Amino-2-(isopropoxymethyl)pteridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 3-Aminopyrazine-2-carbonitrile | HCID 817699 | — |
| Reactant | 2-Isopropoxyacetamidine | HCID 10558602 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-Amino-2-(isopropoxymethyl)pteridine | HCID 10513070 | — |
Reaction Steps
Obtained using the procedure described in section c of Example 2, starting with 8.8 g (0.073 mole) of 3-amino-2-pyrazinecarbonitrile and 13.0 g (0.11 mole) of 2-isopropoxyacetamidine in 295 ml of absolute ethanol. Refluxing time: 4 hours. Yld: 4.5 g (28%), m.p. 139°-141° C. (ethyl acetate).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05167949 |
| Source dataset | uspto-grants-1992_12 |
| ORD ID | ord-b22d3efccd6c4148bec514edc19efc06 |
| Source note | uspto-grants-1992_12 |