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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1681029Generated: October 27, 2026

Ethanol → 2-Isopropoxymethyl-4(3H)-pteridinone

https://huagongshe.com/reaction/1681029

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
Reactant4-Amino-2-(isopropoxymethyl)pteridineHCID 10513070—
SolventSodium HydroxideHCID 14798—
Product2-Isopropoxymethyl-4(3H)-pteridinoneHCID 135528322—

Reaction Steps

Obtained using the procedure described in section d of Example 2, starting with 4.5 g (0.0205 mole) of 4-amino-2-(isopropoxymethyl)pteridine in 150 ml of 5% aqueous sodium hydroxide. Heating time: 2 hours at 80° C. Yld: 3.0 g (66%), m.p. 198°-199° C. (ethanol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05167949
Source datasetuspto-grants-1992_12
ORD IDord-641da57fe52d4aa6954a506b5b6a675d
Source noteuspto-grants-1992_12