Ammonia → 2-(4-Methoxyphenoxy)ethanimidamide

HRID 1681039Notes

Reaction equation

HRID 1681039 reaction equation
[CH3:1][O:2][C:3]1[CH:14]=[CH:13][C:6]([O:7][CH2:8][C:9](=[NH:12])OC)=[CH:5][CH:4]=1.[NH3:15]>C(O)C>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([O:7][CH2:8][C:9]([NH2:12])=[NH:15])=[CH:13][CH:14]=1

Participants

4

Reactant 2

HCID 222Ammonia2×HCID 10655467Methyl 2-(4-methoxyphenoxy)acetimidate

Product 1

HCID 106549552-(4-Methoxyphenoxy)ethanimidamide

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

23.9 g (0.122 mole) of methyl 2-(4-methoxyphenoxy)acetimidate are added to a solution, maintained at 10° C., of 10.4 g (0.61 mole) of ammonia in 480 ml of absolute ethanol. The reaction mixture is left for 2 days at room temperature and the excess ammonia is then driven off with a stream of nitrogen. The solution obtained is used in the next step without further purification.

Workup

  1. customThe solution obtained
  2. customis used in the next step without further purification

Sources & evidence

ORD record
ord-3ea8a36fa8cf408682b452aca0e02b44
Source dataset
uspto-grants-1992_12
Patent number
US05167949

Reaction notes

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