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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 168109Generated: October 26, 2026

1,2-Dichloroethane → 3-(2,2-difluoro-1-hydroxyethyl)-5-(2,4-difluorophenyl)-N-[1-(3-methyl-1,2,4-oxadiazol-5-yl)ethyl]benzamide

https://huagongshe.com/reaction/168109

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantBicarbonate IonHCID 769—
ReactantSodium ionHCID 923—
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
Reactant1-(3-Methyl-1,2,4-oxadiazol-5-yl)ethanamineHCID 43106828—
Reactant5-(2,2-Difluoro-1-hydroxyethyl)-2',4'-difluorobiphenyl-3-carboxylic acidHCID 68498457—
Product3-(2,2-difluoro-1-hydroxyethyl)-5-(2,4-difluorophenyl)-N-[1-(3-methyl-1,2,4-oxadiazol-5-yl)ethyl]benzamideHCID 74817146—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-208c34df8c4c4632873ecbe3a8fe442b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)