Sodium Methoxide → HCID 53691376, compound

HRID 1681118Notes

Reaction equation

HRID 1681118 reaction equation
[CH3:1][O-:2].[Na+].[CH3:4][N:5]([CH3:21])[C:6](=[O:20])[S:7][C:8]1[C:13]2[C:14]([CH3:19])=[CH:15][C:16](=[O:18])[O:17][C:12]=2[CH:11]=[CH:10][CH:9]=1>CO>[OH:2][C:1]1[CH:11]=[CH:10][CH:9]=[C:8]([S:7][C:6]([N:5]([CH3:4])[CH3:21])=[O:20])[C:13]=1[C:14]([CH3:19])=[CH:15][C:16]([O:17][CH3:12])=[O:18]

Participants

4

Reactant 2

HCID 10942334Sodium MethoxideHCID 15714342HCID 15714342, compound

Product 1

HCID 53691376HCID 53691376, compoundYield 76%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

4.4 ml of sodium methylate (8% of Na (w/v) in methanol) are added under an inert atmosphere to a solution of 2 g (7.6.10-3 mol) of S-(4-methyl-2-oxo-2H-1-benzopyran-5-yl) dimethylthiocarbamate in 20 ml of methanol. After 4 hours at room temperature, the reaction medium is hydrolyzed in an ice/hydrochloric acid mixture and the precipitate formed is filtered off to give 1.7 g (yield: 76%) of the expected product.

Workup

  1. customthe precipitate formed
  2. filtrationis filtered off

Sources & evidence

ORD record
ord-cfd617517c8549ad9bdb174c1f392706
Source dataset
uspto-grants-1992_12
Patent number
US05169838

Reaction notes

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