4-Fluorobenzyl bromide → HCID 54408969, compound

HRID 1681181Notes

Reaction equation

HRID 1681181 reaction equation
[F:1][C:2]1[CH:9]=[CH:8][C:5](CBr)=[CH:4][CH:3]=1.[CH2:10]([N:17]1[CH2:22][CH2:21][CH2:20][CH2:19][CH:18]1[CH2:23][OH:24])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[CH2:10]([N:17]1[CH2:22][CH2:21][CH2:20][CH2:19][CH:18]1[CH2:23][O:24][C:5]1[CH:8]=[CH:9][C:2]([F:1])=[CH:3][CH:4]=1)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

3

Reactant 2

HCID 680214-Fluorobenzyl bromideHCID 2735486(1-Benzylpiperidin-2-yl)methanol

Product 1

HCID 54408969HCID 54408969, compound

Procedure

Following the procedure for Example 139, 4-fluorobenzylbromide and 1-benzyl-2-(hydroxymethyl)-piperidine were reacted to give 1-benzyl-2-(4'-fluorophenoxymethyl) piperidine.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-25e8525face14736b6ff3e1bac886378
Source dataset
uspto-grants-1992_12
Patent number
US05169855

Reaction notes

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