3,4-Dichlorophenyl isocyanate → N-[[(3,4-dichlorophenyl)amino]carbonyl]-2-benzofuransulfonamide

HRID 1681208Notes

Reaction equation

HRID 1681208 reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[CH:3]=[C:2]1[S:10]([NH2:13])(=[O:12])=[O:11].[Cl:14][C:15]1[CH:16]=[C:17]([N:22]=[C:23]=[O:24])[CH:18]=[CH:19][C:20]=1[Cl:21]>>[Cl:14][C:15]1[CH:16]=[C:17]([NH:22][C:23]([NH:13][S:10]([C:2]2[O:1][C:5]3[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=3[CH:3]=2)(=[O:11])=[O:12])=[O:24])[CH:18]=[CH:19][C:20]=1[Cl:21]

Participants

3

Reactant 2

HCID 76073,4-Dichlorophenyl isocyanateHCID 107504321-Benzofuran-2-Sulfonamide

Product 1

HCID 21708707N-[[(3,4-dichlorophenyl)amino]carbonyl]-2-benzofuransulfonamideYield 82%

Procedure

2-Benzofuransulfonamide (7.6 mmol), prepared as described in Example 1, was reacted with 3,4-dichlorophenylisocyanate (7.6 mmol) as described in Method A to obtain 2.4 g of the title product as a solid. 1H NMR (CD3SOCD3): δ9.43 (s, 1 H), 7.88 (d, J =8 Hz, 1 H), 7.85 (s, 1 H), 7.80 (m, 1 H), 7.76 (m, 1 H), 7.59 (dd, J =6, 8 Hz, 1 H), 7.52 (d, J =8 Hz, 1 H), 7.45 (dd, J =6, 8 Hz, 1 H), 7.35 (dd, J =3, 6 Hz, 1 H).

Sources & evidence

ORD record
ord-df6526b6cffb4da7ae30accd3d4de07b
Source dataset
uspto-grants-1992_12
Patent number
US05169860

Reaction notes

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