4-Methylphenyl isocyanate → HCID 19807335, compound

Participants

Reaction Steps

The 5-benzofuransulfonamide (5.74 mmol) and 4-methylphenylisocyanate (5.74 mmol) were reacted as described in Method B above to obtain a solid. This residue was purified by reverse phase chromatography with 50% acetonitrile in water with 1% acetic acid on a C18 column to obtain 0.64 g of the title product as a solid. 1H NMR (CD3SOCD3): κ10.35 (bs, 1 H), 8.74 (s, 1 H), 8.38 (d, J =3 Hz, 1 H), 8.20 (d, J =3 Hz, 1 H), 7.96 (dd, J =3, 9 Hz, 1 H), 7.86 (d, J =9 Hz, 1 H), 7.22 (d, J =9 Hz, 2 H), 7.20 (d, J =3 Hz, 1 H), 7.06 (d, J =9 Hz, 2 H), 2.22 (s, 3 H).

Provenance & Evidence