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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 168133Generated: October 30, 2026

Chloride → 4-[1-(tert-butyldimethylsilanyloxy)-2-(1-trityl-1H-imidazol-4-ylmethoxy)ethyl]benzonitrile

https://huagongshe.com/reaction/168133

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantDichloromethaneHCID 6344—
ReactantTriethylsilaneHCID 12052—
ReactantTrimethylsilyl triflateHCID 65367—
ReactantTitanium cation (4+)HCID 114942—
Reactant1-trityl-1H-imidazol-4-ylmethyl (tert-butyldimethylsilyloxy)(4-cyanophenyl)acetateHCID 86632955—
Product4-[1-(tert-butyldimethylsilanyloxy)-2-(1-trityl-1H-imidazol-4-ylmethoxy)ethyl]benzonitrileHCID 66781695—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-3df3762de6114c9b94d1750a2dd3dda0
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)