2-Amino-2-methyl-1,3-propanediol → HCID 19806415, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of trans-stilbene oxide (2.00 g, 0.010 mol) and 2-amino-2-methyl-1,3-propanediol (3.15 g, 0.030 mol) was heated at 150° C. for 3 hours. The reaction mixture was dissolved in 20 mL of methanol and diluted with water to form a white solid. The solid was collected, washed with water and dried for 18 hours under ambient conditions to obtain 2.46 g (82%) of the product. Recrystallization from toluene gave 2.38 g of material; mp 144°-145° C.

Provenance & Evidence