1,1'-Thiocarbonyldiimidazole → HCID 19806557, compound

Participants

Reaction Steps

A mixed solution of 2-amino-3-methyl-5-(4-methylimidazol-1-yl)benzylalcohol (135 mg), N,N'-thiocarbonyldiimidazole (116 mg) and acetone (3.1 ml) was heated under stirring under nitrogen atmosphere for 2 hours. The mixture was distilled under reduced pressure to give a residue. The residue was column chromatographed(chloroform: methanol=30:1) to give 95 mg (59.0%) of the title compound.

Provenance & Evidence