Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Methylimidazole | HCID 12749 | — |
| Reactant | p-Anisoylcyclopropane | HCID 81580 | — |
| Product | HCID 10977186 | HCID 10977186 | — |
Reaction Steps
25 g (0.14 mol) of cyclopropyl 4-methoxyphenyl ketone is combined with 50 g (0.61 mol) of 2-methylimidazole and heated to 225° C. under nitrogen for 16 hr. The reaction is extracted with sodium hydroxide solution and the extract neutralized with ammonium chloride. Recrystallization from methylene chloride/methanol (1:1) provides the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05171858 |
|---|
| Source dataset | uspto-grants-1992_12 |
|---|
| ORD ID | ord-59f2f41d52514aa6b8cdfb7ae1f00826 |
|---|
| Source note | uspto-grants-1992_12 |
|---|
