HCID 13764026, compound → HCID 13764034, compound

HRID 1681422Notes

Reaction equation

HRID 1681422 reaction equation
[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[C:11]3[N:12]([C:16]([CH3:19])=[N:17][CH:18]=3)[CH2:13][CH2:14][CH:15]=2)=[CH:6][CH:5]=1)[CH3:2]>C(Cl)Cl.[O-2].[O-2].[Mn+4]>[CH2:1]([O:3][C:4]1[CH:5]=[CH:6][C:7]([C:10]2[C:11]3[N:12]([C:16]([CH3:19])=[N:17][CH:18]=3)[CH:13]=[CH:14][CH:15]=2)=[CH:8][CH:9]=1)[CH3:2]

Participants

4

Reactant 1

HCID 13764026HCID 13764026, compound

Product 1

HCID 13764034HCID 13764034, compound

Reagents, catalysts & solvents 2

HCID 178418406HCID 178418406, compoundCatalystHCID 6344DichloromethaneSolvent

Procedure

Combine 15 g (59 mmol) of the product of Example IV with 150 g of manganese dioxide in 500 ml of methylene chloride and heat at reflux for 24 hr. Filter off the solids and remove the solvents under vacuum. Crystallize the residue from ethyl acetate to provide the title compound.

Workup

  1. temperatureat reflux for 24 hr
  2. filtrationFilter off the solids
  3. customremove the solvents under vacuum
  4. customCrystallize the residue from ethyl acetate

Sources & evidence

ORD record
ord-375328416ac848b6974387fd42dcaf64
Source dataset
uspto-grants-1992_12
Patent number
US05171859

Reaction notes

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