HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Ethylimidazole → HCID 13810559, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Ethylimidazole | HCID 66130 | — |
| Reactant | Cyclopropyl 4-fluorophenyl ketone | HCID 69876 | — |
| Product | HCID 13810559 | HCID 13810559 | — |
Reaction Steps
Combine 155 g of (0.94 mol) of cyclopropyl-(4-fluorophenyl)methanone with 300 g (3.1 mol) of 2-ethylimidazole and heat to 175° C. under argon for 18 hr. The title compound is isolated by column chromatography on 1500 g of silica gel using 2% methanol/methylene chloride as solvent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05171859 |
| Source dataset | uspto-grants-1992_12 |
| ORD ID | ord-fd14dab6c5c84f0faf5637e7a5dec821 |
| Source note | uspto-grants-1992_12 |