N-bromobutanimide → HCID 13810561, compound

HRID 1681428Notes

Reaction equation

HRID 1681428 reaction equation
[CH3:1][C:2]1[N:6]2[CH:7]=[CH:8][CH:9]=[C:10]([C:11]3[CH:16]=[CH:15][C:14]([N:17]4[CH:21]=[CH:20][N:19]=[C:18]4[CH3:22])=[CH:13][CH:12]=3)[C:5]2=[CH:4][N:3]=1.[Br:23]N1C(=O)CCC1=O>C(Cl)Cl>[Br:23][C:4]1[N:3]=[C:2]([CH3:1])[N:6]2[CH:7]=[CH:8][CH:9]=[C:10]([C:11]3[CH:12]=[CH:13][C:14]([N:17]4[CH:21]=[CH:20][N:19]=[C:18]4[CH3:22])=[CH:15][CH:16]=3)[C:5]=12

Participants

4

Reactant 2

HCID 67184N-bromobutanimideHCID 13764030HCID 13764030, compound

Product 1

HCID 13810561HCID 13810561, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Combine 2.2 g (7.6 mmol) of the product of Example XIV with 1.4 g (7.9 mmol) of N-bromosuccinimide in 50 ml of methylene chloride and stir at room temperature for 1 hr. Wash the reaction with 100 ml of 10% potassium carbonate solution, dry over magnesium sulfate, treat with charcoal, and remove the solvent in vacuo. Crystallize the residue from ether to provide the title compound.

Workup

  1. washWash
  2. customthe reaction with 100 ml of 10% potassium carbonate solution
  3. dry with materialdry over magnesium sulfate
  4. additiontreat with charcoal
  5. customremove the solvent in vacuo
  6. customCrystallize the residue from ether

Sources & evidence

ORD record
ord-d230c6f645f849db8963d785211b36e9
Source dataset
uspto-grants-1992_12
Patent number
US05171859

Reaction notes

Loading…