3-Bromo-5-methylpyridine → 5,6'-Dimethyl-[3,4']bipyridinyl-2'-carboxylic acid (2-chloro-pyridin-4-yl)-amide

HRID 168145Notes

Reaction equation

HRID 168145 reaction equation
[Br:27][c:28]1[cH:29][n:30][cH:31][c:32]([CH3:34])[cH:33]1.[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([NH:8][C:9](=[O:10])[c:11]2[n:12][c:13]([CH3:26])[cH:14][c:15]([B:17]3[O:18][C:19]([CH3:20])([CH3:21])[C:22]([CH3:23])([CH3:24])[O:25]3)[cH:16]2)[cH:7]1>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([NH:8][C:9](=[O:10])[c:11]2[n:12][c:13]([CH3:26])[cH:14][c:15](-[c:28]3[cH:29][n:30][cH:31][c:32]([CH3:34])[cH:33]3)[cH:16]2)[cH:7]1

Participants

3

Reactant 2

HCID 8177133-Bromo-5-methylpyridineHCID 49760409N-(2-Chloropyridin-4-yl)-6-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carboxamide

Product 1

HCID 866145875,6'-Dimethyl-[3,4']bipyridinyl-2'-carboxylic acid (2-chloro-pyridin-4-yl)-amide

Sources & evidence

ORD record
ord-168373e315514b029931a40dd93feeec
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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