Ammonia → HCID 19806695, compound

Participants

Reaction Steps

To a suspension of 3,4-diethoxy-5-cyanoisothiazole-1,1-dioxide (0.85 g, 0.0037 mol) in 40 ml of ethanol was added 2.6 ml of 1.7M ammonia in ethanol (0.0044 mol) with stirring. A clear yellow solution formed and a white precipitate separated in 5 minutes. After 2 hours at room temperature, the title compound (0.61 g, 82%, mp 232°-233.5°) was collected and a sample recrystallized from ethanol to give analytically pure material, mp 236°-238.5°, Rf 0.26 (10% methanol-chloroform, silica gel).

Provenance & Evidence