Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(Triphenylphosphoranylidene)acetaldehyde → 5-(2-Trimethylsilyl-4-furyl)pent-2-en-1-al
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (Triphenylphosphoranylidene)acetaldehyde | HCID 75051 | — |
| 반응물 | 3-(2-Trimethylsilyl-4-furyl)propan-1-al | HCID 15037092 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 5-(2-Trimethylsilyl-4-furyl)pent-2-en-1-al | HCID 57012894 | — |
반응 단계
3-(2-Trimethylsilyl-4-furyl)propan-1-al is treated with (triphenylphosphoranylidene) acetaldehyde in tetrahydrofuran to give 5-(2-trimethylsilyl-4-furyl)-pent-2-en-1-al which is hydrogenated in the presence of a palladium catalyst to give 5-(2-trimethylsilyl-4-yl)-pentan-1-al. Treating this intermediate with C9H19COCH2PO)OCH3)2 and sodium hydride in trimethylsilylfuran and oxidizing gives 4-(7-oxo-5-hexadecenyl)-5-hydroxy-2(5H)-furanone.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05171863 |
| 출처 데이터셋 | uspto-grants-1992_12 |
| ORD ID | ord-0bbca27faaf94e4b965692fb4a400a0f |
| 출처 메모 | uspto-grants-1992_12 |