Potassium Cation → 4-Amino-3-cyano-6-fluoro-5-methoxy-2-methylbiphenyl

HRID 168160Notes

Reaction equation

HRID 168160 reaction equation
[C:1](=[O:2])([O-:3])[O-:4].[C:7](#[N:8])[c:9]1[c:10]([NH:25][C:26](=[O:27])[C:28]([F:29])([F:30])[F:31])[c:11]([O:23][CH3:24])[c:12]([F:22])[c:13](-[c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[c:14]1[CH3:15].[CH3:32][OH:33].[K+:5].[K+:6]>>[C:7](#[N:8])[c:9]1[c:10]([NH2:25])[c:11]([O:23][CH3:24])[c:12]([F:22])[c:13](-[c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[c:14]1[CH3:15]

Participants

5

Reactant 4

HCID 813Potassium Cation2×HCID 887MethanolHCID 19660Carbonate IonHCID 86630810N-(5-cyano-2-fluoro-3-methoxy-6-methylbiphenyl-4-yl)-2,2,2-trifluoroacetamide

Product 1

HCID 860974414-Amino-3-cyano-6-fluoro-5-methoxy-2-methylbiphenyl

Sources & evidence

ORD record
ord-edc941f1875c429cb0b3efaee4499fa7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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