HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-Hydroxy-4-methylaminomethylpiperidine dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 19382193 | HCID 19382193 | — |
| Product | 4-Hydroxy-4-methylaminomethylpiperidine dihydrochloride | HCID 19382178 | — |
Reaction Steps
3 g (13.9 mmol) of ethyl 4-hydroxy-4-methylaminomethylpiperidine-1-carboxylate are heated overnight under reflux with 30 ml of concentrated hydrochloric acid. The product is concentrated, and the crystals are stirred with acetone, filtered off with suction and dried in a vacuum desiccator over P4O10.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05173484 |
| Source dataset | uspto-grants-1992_12 |
| ORD ID | ord-6714f538daa4493bbd8bf2761f34f1d6 |
| Source note | uspto-grants-1992_12 |