Dimethylamine → HCID 19382159, compound

HRID 1681602Notes

Reaction equation

HRID 1681602 reaction equation
[O:1]1[C:3]2([CH2:8][CH2:7][N:6]([C:9]([O:11][CH2:12][CH3:13])=[O:10])[CH2:5][CH2:4]2)[CH2:2]1.[CH3:14][NH:15][CH3:16]>>[CH3:14][N:15]([CH2:2][C:3]1([OH:1])[CH2:8][CH2:7][N:6]([C:9]([O:11][CH2:12][CH3:13])=[O:10])[CH2:5][CH2:4]1)[CH3:16]

Participants

3

Reactant 2

HCID 674DimethylamineHCID 13672926Ethyl 1-oxa-6-azaspiro[2,5]octane-6-carboxylate

Product 1

HCID 19382159HCID 19382159, compound

Procedure

5.2 g (28 mmol) of ethyl 6-aza-1-oxaspiro[2,5]octane-6-carboxylate are added dropwise to 30 ml of dimethylamine solution (40% in water ) and the mixture is stirred overnight at room temperature. It is then concentrated and distilled.

Workup

  1. concentrationIt is then concentrated
  2. distillationdistilled

Sources & evidence

ORD record
ord-4ec812f6a6b14988bdc5f76b6568a65c
Source dataset
uspto-grants-1992_12
Patent number
US05173484

Reaction notes

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