Ethylamine → HCID 19382186, compound

HRID 1681604Notes

Reaction equation

HRID 1681604 reaction equation
[O:1]1[C:3]2([CH2:8][CH2:7][N:6]([C:9]([O:11][CH2:12][CH3:13])=[O:10])[CH2:5][CH2:4]2)[CH2:2]1.[CH2:14]([NH2:16])[CH3:15]>>[CH2:14]([NH:16][CH2:2][C:3]1([OH:1])[CH2:8][CH2:7][N:6]([C:9]([O:11][CH2:12][CH3:13])=[O:10])[CH2:5][CH2:4]1)[CH3:15]

Participants

3

Reactant 2

HCID 6341EthylamineHCID 13672926Ethyl 1-oxa-6-azaspiro[2,5]octane-6-carboxylate

Product 1

HCID 19382186HCID 19382186, compound

Procedure

5.7 g (30.8 mmol) of ethyl 6-aza-1-oxaspiro[2,5]octane-6-carboxylate are added dropwise to 30 ml of ethylamine solution (50% in water) and the mixture is stirred overnight at room temperature. It is then concentrated and distilled.

Workup

  1. concentrationIt is then concentrated
  2. distillationdistilled

Sources & evidence

ORD record
ord-9cb734b3730a4d4f9348b368b1e21904
Source dataset
uspto-grants-1992_12
Patent number
US05173484

Reaction notes

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