反应详情

10 g (45 mmol) of 1-benzyl-3-hydroxy-3-methoxymethylpyrrolidine are hydrogenated using 3 g of Pd/active carbon (10% Pd) in 200 ml of methanol at 100° C. and 100 bar. The catalyst is filtered off with suction, the filtrate is concentrated and the residue is distilled.

1. customat 100° C.
2. filtrationThe catalyst is filtered off with suction
3. concentrationthe filtrate is concentrated
4. distillationthe residue is distilled