Ammonium → HCID 18955298, compound

HRID 1681658Notes

Reaction equation

HRID 1681658 reaction equation
C[O:2][C:3]([CH2:5][N:6]1[C:13]2[N:9]([N:10]=[CH:11][CH:12]=2)[CH2:8][CH2:7]1)=O.[NH4+:14]>C(O)C>[C:3]([CH2:5][N:6]1[C:13]2[N:9]([N:10]=[CH:11][CH:12]=2)[CH2:8][CH2:7]1)(=[O:2])[NH2:14]

Participants

4

Reactant 2

HCID 223AmmoniumHCID 18955286HCID 18955286, compound

Product 1

HCID 18955298HCID 18955298, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of 1-methoxycarbonylmethyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazole (27 g) in ethanol (135 ml) was added 28% ammonium solution (100 ml). The mixture was stirred overnight at room temperature. The insoluble material was filtered off and the filtrate was evaporated to precipitate the crystals. The crystals were collected by filtration to give 1-carbamoylmethyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazole (6 g).

Workup

  1. filtrationThe insoluble material was filtered off
  2. customthe filtrate was evaporated
  3. customto precipitate the crystals
  4. filtrationThe crystals were collected by filtration

Sources & evidence

ORD record
ord-670bad35a6f9432d92b0f722e922728a
Source dataset
uspto-grants-1992_12
Patent number
US05173485

Reaction notes

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