Boron tribromide → HCID 19805511, compound

HRID 1681702Notes

Reaction equation

HRID 1681702 reaction equation
[CH2:1]([N:8]1[C:16](=[O:17])[C:15]2[C:10](=[CH:11][C:12]([O:18]C)=[CH:13][CH:14]=2)[NH:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.B(Br)(Br)Br>>[CH2:1]([N:8]1[C:16](=[O:17])[C:15]2[C:10](=[CH:11][C:12]([OH:18])=[CH:13][CH:14]=2)[NH:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 25134Boron tribromideHCID 19805449HCID 19805449, compound

Product 1

HCID 19805511HCID 19805511, compoundYield 21%

Procedure

Using an analogous procedure to that described in Examples 48-51 treatment of 1,2-dihydro-2-benzyl-6-methoxy-3H-indazol-3-one (Ex. 174) with boron tribromide gave 1,2-dihydro-2-benzyl-6-hydroxy-3H-indazol-3-one as a solid, m.p. 206-207° C. in 21% yield.

Sources & evidence

ORD record
ord-1af56c37e2344c119ac2f68dec6d86f9
Source dataset
uspto-grants-1992_12
Patent number
US05173496

Reaction notes

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