Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | 2-Methylimidazole | HCID 12749 | — |
| Reactant | HCID 10465751 | HCID 10465751 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 10334592 | HCID 10334592 | 30.4% |
Reaction Steps
A mixture of 8,9-dihydro-10-methyl-7-methylenepyrido[1,2-a]indol-6(7H)-one (142 mg), 2-methylimidazole (180 mg), isopropyl alcohol (1 ml) and water (0.4 ml) was heated at 100° C. for 3 hours. The reaction mixture was purified by a procedure analogous to that of Example 74 to give 8,9-dihydro-10-methyl-7-[(2-methyl-1H-imidazol-1-yl)methyl]pyrido[1,2-a]indol-6(7H)-one (60 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05173493 |
|---|
| Source dataset | uspto-grants-1992_12 |
|---|
| ORD ID | ord-ac7ebf912231497380230df1d44b1ab7 |
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| Source note | uspto-grants-1992_12 |
|---|
